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Chunk #19 — Results

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Association of single nucleotide polymorphisms in a glutamate receptor gene (GRM8) with theta power of event-related oscillations and alcohol dependence.
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Table 2 demonstrates p-values of the results of the FBAT with the theta band EROs as well as diagnoses of alcohol dependence. Multiple significant genetic associations (p<0.05) were identified with theta band of ERO and the SNPs in the intron 6 and intron 7 of GRM8. Of note, 3 SNPs, rs1361995, rs10487457, rs10487459, in the intron 6 region were significantly associated with both the quantitative trait phenotype, theta band of EROs, and the ICD-10 diagnostic criteria of alcohol dependence.