Experiencing psychosocial stress early in life likewise predisposes individuals to cognitive dysfunction, addiction, and increased prevalence rates of psychiatric disorders (Enoch, 2011; Gilbert et al., 2009; Schenkel et al., 2005; Shea et al., 2005). While these stressful experiences occur early, behavioral outcomes often do not manifest until later in life. For example, disorders including posttraumatic stress disorder (PTSD), depression, and schizophrenia that have increased prevalence rates among individuals with a history of early-life stress (Kendall-Tackett, 2002; Schenkel et al., 2005; Weiss et al., 1999) typically emerge during adolescence or adulthood (Adriani and Laviola, 2004; Agid et al., 1999; Costello et al., 2003; Holmes, 2013). Epigenetic mechanisms have emerged as a mediating factor between early stress and its outcomes, both immediate and latent (Kundakovic and Jaric, 2017; Lewis and Olive, 2014; McGowan and Roth, 2015; Roth, 2012, 2013; Roth et al., 2009b; Roth and Sweatt, 2011; Silberman et al., 2016; Tsankova et al., 2007). Common targets of the effects of early-life stress include the prefrontal cortex (Kolb et al., 2017), hippocampus (Fenoglio et al., 2006), amygdala (Cohen et al., 2013), and
