We also examined the overlap between cis eQTLs in GHS and cis-heritable eQTLs found by expression profiling of lymphocyte RNA in the San Antonio Family Heart Study (SAFHS) 4. Among the eQTLs with a cis heritability ≥0.1 in SAFHS, 62% were significantly cis modulated in GHS, and this proportion reached 89% for heritabilities ≥0.6 ( Figure 3 , File S5).
