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Chunk #67 — Methods/Design — Genetic ancestry

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Protocol for a collaborative meta-analysis of 5-HTTLPR, stress, and depression.
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Our analyses will stratified by genetic ancestry (European, Asian, African, Pacific Island, and Admixed European-African). The majority of data is from participants of European ancestry and there may be limited power to detect ethnic heterogeneity in the results. If there is sufficient power to effectively test for heterogeneity and none is found, then a meta-analysis across all ancestry groups will be evaluated.