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Chunk #20 — RESULTS — Human PET-study

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A genetic determinant of the striatal dopamine response to alcohol in men.
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BACs at the end of the alcohol infusion during the PET session were, on average, within 1 mg/dl of the target level, confirming the high level of accuracy and precision of the method. There were no differences between BACs achieved in the AA and AG groups (ANOVA: F[1, 24]=0.287, p = 0.597). Baseline binding potential (BP) for [11C]-raclopride, as measured on the saline infusion session, also did not differ between genotypes (AA: 3535.8±107.8; AG: 3722.7±124.5 nCi/cc, mean±SEM; F[1,26]=1.3, p=0.27), making pre-existing differences in D2 receptor densities unlikely.