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Chunk #4 — Introduction

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Mechanisms in the relation between GABRA2 and adolescent externalizing problems.
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Taken together, previous research suggests that GABRA2 relates to some facets of disinhibition and these facets at least partially mediate the effect of GABRA2 on externalizing problems. However, no studies to our knowledge have examined which facets of disinhibition mediate the relation between GABRA2 and adolescent conduct problems, alcohol problems, and hyperactive–inattentive symptoms.