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Chunk #33 — Discussion

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Genome-wide association study in obsessive-compulsive disorder: results from the OCGAS.
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and CDH9/CDH10. The finding that the signals in this GWAS concur with respect to allele and direction significantly with the top signals in a second reported OCD GWAS, suggests that similar genetic underpinnings of OCD are identified in both studies. Moreover, while not a replication in the full sense, findings for the genes DLGAP1 and GRIK2 suggest that they are both relevant candidates genes for OCD. The suggestive findings in this study await replication in larger samples.