zero and were polymorphic in two or more ancestry-stratified cohorts to ease interpretation of heterogeneous effects. For example, a variant in which the model with two components best fit the data was considered at least weakly heterogeneous. If this variant also had a component two effect significantly different than zero (\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$${\gamma }_{j2}\ne 0,$$\end{document}γj2≠0, from above) and was polymorphic in at least two ancestries, it was considered strongly heterogeneous.
