The distribution of CNVs conferring susceptibility across the four disorders was characterized using Venn diagrams for CNV groupings and gene groupings. These data for strict criteria are shown in Figure 1 and Table S2, available online. ID had the largest grouping of CNVs out of all DSM disorders (27 of 54, 50% of CNVs) and these CNVs were the most gene rich (27 of 44, 61.4% of genic CNVs which encompassed 1,198 of 1,416 or 84.6% of total genes). As a consequence, one striking result of this study is that, based on gene distributions, all disorders were largely subsumed by the ID gene group even for the strict criteria (Figure 1A). This pattern was supported also when gene groupings were separated into those implicated by deletions or duplications (Figure 1B and 1C). With the distribution of genes across disorders using strict criteria, ID was associated to an even greater degree with 96.8% (244 of 252) of genes in ASD, 92.8% (386 of 416) of genes in schizophrenia, and 100% (111 of 111) of genes in epilepsy. Broad criteria again demonstrated
