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Chunk #31 — Procedures — Identification of De Novo CNVs

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High frequencies of de novo CNVs in bipolar disorder and schizophrenia.
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yes

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directly genotyped using the MeZOD, and a confidence score was used to assign genotypes to the parents. Rare CNVs in children were called inherited if the CS was ≤ 0.04 in either of the two biological parents and de novo if CS was > 0.04 in both biological parents. We identified 145 putative de novo CNVs in 788 subjects including BD, SCZ, and controls.