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Chunk #10 — Materials and Methods — Assessment

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Association of PER2 genotype and stressful life events with alcohol drinking in young adults.
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Stressful life events were assessed with a modified and shortened version of the Munich Events List (MEL) [31]. The questionnaire asked for occurrence and threat of severe life events and chronic difficulties in the four years prior to the assessment in young adulthood. The items addressed all areas of a young adult’s life from school to job, partner, family, parents, living conditions, legal troubles, up to health problems. Threat was rated on a scale ranging from 1 (not stressful) to 5 (very heavy stress). The total score of acute severe life events was calculated as the sum of 38 items, referring to events with acutely stressful impact, such as the death of a loved one or relationship breakup, which rated at a stress level of 3 (considerably stressful) or more. In this sample, the score ranged from 0 to 15 events (M = 2.86, SD = 2.60). Psychometric characteristics of the MEL have been confirmed in several studies [32].