We tested for associations between our 97 BMI-associated index SNPs and other metabolic phenotypes (Supplementary Tables 13–15 and Extended Data Figs 5 and 6). Thirteen of the twenty-three phenotypes tested had significantly more SNPs with effects in the anticipated direction than expected by chance (Supplementary Table 16). These results corroborate the epidemiological relationships of BMI with metabolic traits. Whether this reflects a common genetic aetiology or a causal relationship of BMI on these traits requires further investigation.
