paperKB
coga / coga-kb
Help
Sign in

Chunk #3 — Methods

Source
Genetic analysis of the maximum drinks phenotype.
Embedded
yes

Text

in this interval from the combined Illumina and Affymetrix sets were analyzed for trait association using the quantitative pedigree disequilibrium test (QPDT) [2] as implemented in the program UNPHASED [3]. Our choice to use the Illumina SNP set (4,710 markers) for the first stage and the Affymetrix SNP set (11,120 markers) together with the Illumina set for the follow-up association analysis allowed us to carry out the initial genome screen and then proceed with fine-mapping in regions of linkage using the more densely spaced SNPs provided by Affymetrix.