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Chunk #9 — Materials and methods — Weights for genetically predicted mRNA, protein, and splicing

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Multiomic prioritisation of risk genes for anorexia nervosa.
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the GTEx v7 and PsychENCODE studies above, the DLPFC SNP weights were estimated using the HapMap3 panel, and thus, we only used those SNPs as an LD reference. The plasma PWAS utilised the full reference panel. Finally, the splicing related weights were derived from the DLPFC samples from the Common Mind Consortium (N = 452) which utilised the HapMap3 restricted 1000 genomes panel (Gusev et al., 2018).