Let γ=hm2/hf2 denote the dosage compensation ratio. The ratio takes on a value between 0.5 (zero dosage compensation) and 2 (full dosage compensation). Based on the above equation, we estimated it as γ^=(χ^m2−1)Nf(χ^f2−1)Nm, where χ^i2 is the mean χ2 statistic. (Equivalently, our γ estimate is equal to the ratio of our SNP heritability estimates.)
