paperKB
coga / coga-kb
Help
Sign in

Chunk #4 — Introduction

Source
Event-Related Theta Power during Lexical-Semantic Retrieval and Decision Conflict is Modulated by Alcohol Intoxication: Anatomically Constrained MEG.
Embedded
yes

Text

The present study was designed to integrate and expand on these findings in several ways. First, in order to investigate whether the effects of alcohol were specific to lexical-semantic processing, we employed a lexical decision task in which participants were asked to detect visually presented real words among non-words. Second, the lexical decision task was embedded in a double-duty paradigm that included an additional requirement to detect all real words that also referred to animals. By manipulating conflicting demands in the context of lexical-semantic retrieval, this task modification allowed us to examine the effects of acute intoxication on both language and executive functions. Third, the whole-head magnetoencephalography (MEG) signal was analyzed with a Time–Frequency (TF) method, providing an insight into the oscillatory dynamics of the distributed network subserving visual word processing. In an effort to examine where the conflict- and beverage-specific brain oscillatory changes are occurring and to gain insight into the temporal sequence (“when”) of the involved neural components, we have employed a multimodal neuroimaging methodology. The anatomically constrained MEG (aMEG) analysis stream combines distributed source modeling of the