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Chunk #25 — How can genetics inform neurobiology?

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The psychiatric GWAS consortium: big science comes to psychiatry.
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Historically, there has been a gap between psychiatric genetics and neuroscience. In an idealized universe, psychiatric genetics and neuroscience would have rather symbiotic relations. In this way, we may well find that a genetic, molecular, or neuronal process being studied in a lab for one set of reasons ends up emerging as a potentially critical factor for a psychiatric disorder, based on genetic data. Ultimately, it's this kind of synergy, between genetics and biology, which will pave the path to true understanding of how genotype confers risk for phenotype and gives us the best chance of really understanding these disorders and paving the way for more effective therapies.