Chunk #38 — Glossary

Source

Polygenic risk scores in psychiatry: Will they be useful for clinicians?

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yes

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Causal variant: Causal variants have a direct biological effect and a direct effect on the phenotype. Causal variants are responsible for the association signal at a locus, although the association may be identified by using other non-causal variants in linkage disequilibrium with the causal variant.