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Chunk #16 — Method — Data Preprocessing

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Externalizing psychopathology and gain-loss feedback in a simulated gambling task: dissociable components of brain response revealed by time-frequency analysis.
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The data were averaged across trials within monetary condition (Gain versus Loss trials), and epochs were baseline-corrected for the 150 ms preceding feedback stimulus presentation. A careful visual inspection of the data was undertaken to identify and exclude movement and other artifacts, in particular, to minimize their impact on the time-frequency PCA decomposition (detailed below). Toward this end, several exclusionary criteria were applied. First, to exclude ocular artifacts remaining after ocular correction, trials on which activity at frontal electrode sites F1 or F2 exceeded 75 μV within a 1500 ms post-stimulus window (relative to median activity within a 750 ms window immediately preceding the stimulus) were excluded from further processing. Then, within each trial, individual electrode sites at which activity exceeded ± 75 μV in either the pre- (−750 to 0) or post-stimulus (0 to 1500) time regions (relative to one another) were also omitted from analysis. Applying these criteria, 9.9% of trials were excluded. Additionally, across all subjects and electrodes, 24 subject-electrodes (out of 8517) became disconnected at some point during the procedure. Missing data for these leads were