Bin C, a group of 82 variants correlated in Europeans, consisted of 24 sub-bins in subjects of Asians and 26 sub-bins in African Americans. Variants reported in previous meta-analyses of European ancestry (rs6495308 [Liu, et al. 2010], rs2036534 [Thorgeirsson, et al. 2010], rs7163730, rs9788682, rs684513 [TAG 2010], rs578776 [Saccone, et al. 2010]) were all examined. However, no tested SNP in bin C was consistently associated with heavy smoking with p < 0.01 in both Asians and African Americans. Similarly, we have no consistent associations with bin D which contains 15 SNPs correlated in Europeans and consists of 7 sub-bins in Asians and 7 sub-bins in African Americans.
