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Chunk #38 — Methods — — Statistical analyses.

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Analysis and application of European genetic substructure using 300 K SNP information.
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Fst was determined using Genetix software [38] that applies the Weir and Cockerham algorithm [39], and δ was calculated by determining the absolute value of the allele frequency difference between two populations. A measure of informativeness for each SNP (In) was determined using an algorithm previously described [22]. Linkage disequilibrium was examined using the Genetix software [38]. False discovery rate statistics [14] were determined using HelixTree 5.0.2 software (Golden Helix, Bozeman, MT, USA).