history of substance dependence. A subgroup of FSCD subjects was not alcohol dependent, but had a lifetime diagnosis of DSM-IV cannabis dependence or dependence on another illicit drug. COGEND subjects were recruited in MO and MI. Cases met criteria for DSM-IV alcohol and/or ND. SAGE samples were genotyped on the Illumina Human 1M array containing 1,069,796 total SNPs. Control subjects were selected from the non-dependent population and did not meet criteria for AD, ND, or illicit DD.
