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Chunk #11 — Materials and methods — Data used in this study — Gene expression data

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Integration of summary data from GWAS and eQTL studies identified novel causal BMD genes with functional predictions.
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We used previously published gene expression profile generated from PBMs [36] to generate gene co-expression networks to assess the potential interactions and thus potential mechanisms for the identified novel gene. PBMs were from 73 Caucasians females, which were stratified by hip BMD and menopausal status. In the high BMD group there were 42 subjects with 16 premenopausal and 26 postmenopausal women. In the low BMD group there were 31 subjects with 15 premenopausal and 16 postmenopausal women. Details of the samples’ information can be found in the previous study [32]. We downloaded the raw data under the accession number GSE56814 from Gene Expression Omnibus (GEO) website.