Overall, 70% of the factors were associated with reduced coherence for the ASD- population. Furthermore, two of the four most utilized factors by DFA, including the most frequently selected Factor 15, were characterized by reduced ASD coherence. Moreover, seven of the eight factors characterized by short inter-electrode distance and all five of the factors representing a mix of short and long distance coherences were associated with reduced coherence. This study is not, of course, the first to report evidence for reduced coherence in ASD [22,23,25,27,28]. Such a preponderance of reduced coherence in ASD suggests likely corresponding reduction in cortical connectivity and corresponding lack of interactions between cortical regions. Some authors attribute ASD primarily to reduced integration of brain activity where specialized cortical regions are anatomically and functionally poorly connected with one another [17,72-76]. Indeed, the most consistently selected factor in the current study (Factor 15) exclusively demonstrated reduced connectivity primarily between the posterior and anterior left temporal regions, and between the left anterior temporal and left frontal regions - and to a degree in the right anterior temporal region. Broadly,