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Chunk #19 — Results — AspPS predictivity in admixed genomes

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Ancestry deconvolution and partial polygenic score can improve susceptibility predictions in recently admixed individuals.
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the trait-SNP associations discovered in Europeans is greater than zero and (B) the directional bias in PS introduced by the non-European genetic component is moderate. Nonetheless, this result confirms that the genomic portion discarded by the local ancestry deconvolution only adds, indeed, a negligible amount of information: this is further substantiated by the poor performance achieved by a control where the local ancestry patterns were randomly assigned by design, see Supplementary Fig. 6.