Individuals with 0–1, 2 and ≥3 lifetime symptoms were similar in age but their life situations, as reflected in their educational, work and marital status at the time of interview, were very different (Table 1). Individuals with two or more lifetime AUD symptoms had less education, were less likely to have children, and were more likely to be separated or divorced, or to live as though married, than were individuals with just 0–1 symptoms. In addition, these individuals reported an earlier onset of alcohol problems, as reflected in younger ages at regular drinking and onset of first AUD symptom, and a larger maximum number of drinks consumed in a 24-h period (Table 1). The co-twins of twins with two or more symptoms were more likely to report them as having alcohol problems than were co-twins of twins with 0–1 symptoms. Individuals with three or more symptoms were more likely to report alcohol problems in one or both parents.