with autism (data not shown). Exhaustive molecular analysis of the candidate region is ongoing. In addition, although the immediate 1 Mb vicinity of the association region contains no known genes, flanking the region are CDH9 and CDH10, two genes belonging to the cadherin family, a group of proteins containing members that are involved in calcium-dependent cell-cell junctions in the nervous system (Liu et al. 2006, Pokutta, Weis 2007) and possible targets of regulatory action.