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Chunk #26 — Discussion

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A genome-wide association study of autism reveals a common novel risk locus at 5p14.1.
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with autism (data not shown). Exhaustive molecular analysis of the candidate region is ongoing. In addition, although the immediate 1 Mb vicinity of the association region contains no known genes, flanking the region are CDH9 and CDH10, two genes belonging to the cadherin family, a group of proteins containing members that are involved in calcium-dependent cell-cell junctions in the nervous system (Liu et al. 2006, Pokutta, Weis 2007) and possible targets of regulatory action.