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Chunk #11 — Results — Differential spatial and temporal connectivity

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Multiple interacting brain areas underlie successful spatiotemporal memory retrieval in humans.
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As shown in Figure 4D, betweenness centrality indicated that the SPL and visual cortex had high betweenness centrality for the difference between spatial and temporal (spatial – temporal, see Methods) compared to the temporal – spatial retrieval networks (all pcorrected < 0.05, SPL: χ2 (1) = 15.41 and primary visual cortex: χ2 (1) = 20.15). Conversely, MFG and IFG nodes, located in the anterior portion of the brain, had higher betweenness centrality for temporal – spatial (all pcorrected < 0.05, MFG: χ2 (1) = 9.90, IFTr: χ2 (1) = 35.90, IFOp: χ2 (1) = 20.43, Fig. 4E). However, the MTL nodes showed levels of connectivity significantly greater than zero for both spatial and temporal order retrieval, indicating significant levels of connectivity during both forms of retrieval. Importantly, though, they exhibited no significant differences in their levels of connectivity for spatial versus temporal (all pcorrected > 0.05, aHPC: χ2 (1) = 4.30, pHPC: χ2 (1) = 4.14, pPHG: χ2 (1) = 0.11). Additionally, the node hierarchies in the right panels of Figure 4A,B emphasize a similar level of connectivity and betweenness