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Chunk #5 — 2. METHODS — 2.1 University Of Wisconsin Transdisciplinary Tobacco Use Research Center (Uw-Tturc) Trial

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Genetic variation (CHRNA5), medication (combination nicotine replacement therapy vs. varenicline), and smoking cessation.
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Participants were eligible if they were 18 years of age or older, and smoked 10 or more cigarettes per day (Piper et al., 2009). The University of Wisconsin-Madison IRB approved this trial, and all subjects provided written informed consent. Participants (N = 328) were randomly assigned to either placebo (n = 135) or cNRT (nicotine patch and nicotine lozenge, n =193) for 8 weeks. Additional arms in this trial, not analyzed in this analysis, included nicotine patch, nicotine lozenge, bupropion SR, and bupropion/nicotine lozenge (n = 747). All participants received individual counseling.