The PhenX project is led by RTI International (Research Triangle Park, North Carolina) and is funded by the National Human Genome Research Institute (Bethesda, Maryland) at the National Institutes of Health (NIH). The goal of PhenX is to identify and catalog 15 high-quality, low-burden, well-established measures and accompanying standard protocols for each of 21 research domains. The PhenX measures are available to the scientific community via a Web-based toolkit (https://www.phenxtoolkit.org/).