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Chunk #14 — Materials and Methods — Pathology review

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A Novel Approach to High-Quality Postmortem Tissue Procurement: The GTEx Project.
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After tissues were sectioned and stained at the CBR, tissue sections were scanned using a digital whole slide imaging system (Aperio).7 The PRC pathologists were able to review these images remotely via an Internet web portal. The PRC assessed and generated a report on multiple parameters, including verifying that the correct target tissue has been obtained and is of the correct size; the degree of autolysis; the presence of clinically unsuspected malignancy or infection; and the presence of significant “contaminant” but normal adjacent tissue, such as excessive adherent fat around an aliquot.