Figure 5 provides an example of the information displayed on the study-locus page. In this example, we are investigating an Inflammatory Bowel Disease susceptibility locus defined by 2_181443625_A_G where the alternative allele (G) is protective (22). The first section (Figure 5A) displays the genes prioritised at this locus by the L2G analysis pipeline, with a breakdown of the individual predictors to show the score each gene would receive in a model including a single predictor category. The second section displays the genes prioritised at this locus using the colocalisation pipeline as a table (Figure 5B) or as a heatmap (Figure 5C). The third section displays GWAS traits and diseases that colocalise at this locus (Figure 5D). The final section provides the set of likely causal variants (credible sets) at this locus together with a regional plot view and enables the user to look at credible sets overlap between this study and other GWAS and QTL studies that colocalise at this locus (Figure 5E).
