Exploratory analyses showed that amongst fast metabolizers, combination NRT (patch + lozenge) produces lower relapse rates than does NRT monotherapy (HR=0.61, 95%CI=0.42-0.89, p=0.011). The lozenge and patch did not significantly differ from one another (HR=0.69, 95%CI=0.45-1.05, p=0.083). The effects of the NRT subtypes did not differ amongst the slow metabolizers.
