increased exonic H3K9 acetylation and DNA methylation ( Fig. 3b–c ). Previous studies have examined the relationships between differences in DNA methylation and histone acetylation and gene expression in on/off states of gene expression activity, as seen in cancer and cellular differentiation paradigms[23], [25], [26], [27], [29]. Our data suggest that the modulation of gene expression in response to environmental stimuli follows the same rules.
