Our study database did not contain patient identifiable information. To protect the privacy of individual patients, physicians and hospitals, the state and hospital identifiers were all de-identified; this database is available as a public database. The use of this administrative database under the HCUP, according to the Agency for Healthcare Research and Quality (AHRQ) of the U.S. Department of Health and Human Services, does not require approval from an Institutional Review Board (IRB), because the NIS is publicly available and is a fully de-identified database.