The differences in initial response by ALDH2 and GABRA2 genotypes were analyzed by analysis of variance (ANOVA), whereas the data for acute adaptation were examined using repeated measures ANOVA. We compared the differences in initial response and acute adaptation among subjects with different genotypes of 7 GABRA2 SNPs divided by ALDH2 genotype because ALDH2 genotype has been proved to have strong effects on the level of response to alcohol (Cook et al., 2005; Luczak et al., 2002; Wall et al., 1999).
