Chunk #140 — Quantification and Statistical Analysis — Transcriptional Activity Score (TAS)

Source

A Next Generation Connectivity Map: L1000 Platform and the First 1,000,000 Profiles.

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yes

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The transcriptional activity score (TAS) is computed as the geometric mean of SS and CC for a signature. TAS is scaled by the square root of the number of landmark genes (978) so the final score ranges between 0 and 1.