We genotyped the prioritized SNPs in a Finnish case-control sample (Supplementary Table 1; Supplementary Methods) using the Sequenom Homogeneous Mass EXTEND or iPLEX Gold SBE assays, carried out at the National Human Genome Research Institute (NHGRI). 59 SNPs had genotype call frequency >94% and HWE p value >0.001. The genotype consistency rate among 56 duplicate samples was 100% and the average call frequency of successfully genotyped SNPs was 97.3%. SNPs were analyzed using logistic regression with adjustment for sex, 5-year age category and birth province and an additive model for the genetic effect.
