To further replicate our GWAS findings in Caucasians, we used a sample from the FHS population, which contains 7,623 Caucasians, including 3,491 males and 4,132 females, from 1,731 families. The phenotype and genotype information of the cohort was downloaded from Framingham SHARe (SNP Health Association Resource), accessed through NCBI dbGaP (http://view.ncbi.nlm.nih.gov/dbgap). Appropriate procedures have been taken for the usage of the data, which include approval from UMKC IRB and signatures on the Data Distribution Agreement by all the UMKC investigators who have access to the data.
