Green et al. [34] described relationships between white matter microstructure and reaction time during prosaccades (eye movement towards a peripheral stimulus) and antisaccades (eye movement away from a peripheral stimulus) in children with FASD. Lower FA in the cerebellum was related to slower reaction times during prosaccades. However, lower FA in the genu of the corpus callosum and the inferior longitudinal fasciculus was related to faster reaction times during prosaccades, and in a large portion of the right corpus callosum lower FA was related to faster reaction time on antisaccades. The authors speculated that the negative relationship between FA in the corpus callosum and inferior longitudinal fasciculus and reaction times may be due factors that artificially inflate FA, such as a reduced dispersion or branching of axons within a voxel.
