Measures of modularity (Q) were high, and did not show large changes across the age range (Figure 3A and Figure S1 and Figure S2). This result was not dependent on any particular threshold (Figure S1). Although comparable community structure was detected at all ages examined, the components of the communities varied by age. As per our qualitative approach described above, in children, region clusters were largely arranged by cerebral lobe; while in adults, regions were largely clustered by their adult functional properties (Figure 4A). Again, this result was not unique to any particular threshold (Figure 4B and 4C) or size of boxcar (Figure S3). We do note, however, that limited data points (i.e., subjects) are available between the ages of 16 and 19 years (see Materials and Methods) and that our estimate of the specific transitions within this period should be interpreted with care.
