Multi-investigator research consortia have also been used to study the genetic architechture of SUD. These consortia-based genetic association studies aggregate GWAS data from individual studies in order to address the need to increase sample size and improve power to detect significant associations. Consortia-based genetic association studies often use meta-analyses and report summary data submitted across studies or analyze raw data from multiple GWASs (Panagiotou et al., 2013).