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Chunk #8 — IMPROVED DATA CURATION

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The new NHGRI-EBI Catalog of published genome-wide association studies (GWAS Catalog).
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GWAS Catalog data are manually extracted from the literature and entered via a curation interface. The curation interface supports all aspects of the process, including progress reporting, tracking of studies, data entry and quality control. We have re-developed and deployed this interface at the EMBL-EBI focusing on ease of navigation, usability and scaling of curation processes. The curation homepage provides summary information and tracking for all studies within the GWAS Catalog, while the study-specific data entry pages now have separate tabs for study, sample, association and curator information. Additional tabs have been added to allow curators to attach and directly access files relating to the study (e.g. PDF of publication and supplementary materials), print all study-specific information and view provenance information for study-specific data entry. Direct mapping of traits to the Experimental Factor Ontology (EFO) at both the study and association level, is available within the curation interface, facilitating mapping within the curation workflow. These improvements will support future scaling of curatorial activities through author deposition, as discussed in future work.