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Chunk #0 — Introduction

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Genome-wide association analyses suggested a novel mechanism for smoking behavior regulated by IL15.
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Cigarette smoking results in an annual death toll of 438,000 in the United States, where one in every five deaths is smoking related (1). Smoking is highly associated with the development of cardiovascular and respiratory diseases, and cancer (2). Most dramatically, men and women who smoke increase their risk of developing lung cancer by 13 and 23 folds, respectively, compared to non-smokers (2).