Chunk #21 — Results — Assessment of mRNA:miRNA module interactions in AD

Source

Integrating mRNA and miRNA Weighted Gene Co-Expression Networks with eQTLs in the Nucleus Accumbens of Subjects with Alcohol Dependence.

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to an enhanced repressive effect and greater specificity of target regulation [54]. The most prominent case of such cooperative targeting by miRNAs was for AF4/FMR2 family, member 1 (AFF1), which was targeted by 8 miRNAs from miRNA: M blue and M yellow. The full list of the 481 significant negatively correlated and bioinformatically predicted miRNA:mRNA targeting pairs is given in S7 Table.