Chunk #3 — Background

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Description of the data from the Collaborative Study on the Genetics of Alcoholism (COGA) and single-nucleotide polymorphism genotyping for Genetic Analysis Workshop 14.

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The Affymetrix mapping 10k assay [13-15] is an innovative approach that enables rapid typing of 11,560 SNP markers on an array using a single PCR primer and only 250 ng of genomic DNA. The Affymetrix assay uses allele specific hybridization.