paperKB
coga / coga-kb
Help
Sign in

Chunk #82 — Online Methods — Estimating the correlation matrix C.

Source
Flexible statistical methods for estimating and testing effects in genomic studies with multiple conditions.
Embedded
yes

Text

where N:={j :maxr|zjr|<2}For the GTEx data, we found that measurements in different tissues were not highly correlated; all elements of estimated C had magnitude less than 0.2, and 95% had magnitude less than 0.1. However, in cross-validation tests (below), this estimated C produced better model fit than ignoring correlations (i.e., C = IR).