Data were analyzed using SPM2 software (Wellcome Department of Imaging Neuroscience, University College, London, UK), with both placebo and alcohol session preprocessed together. Functional images volumes were slice-timed and realigned to the mean functional image volume. After co-registration to the mean functional image volume, each subject’s anatomic image was normalized to stereotactic (MNI) space using the default SPM template. The normalization parameters were then applied to the previously realigned functional images volumes. Finally, the BOLD images were smoothed with an 8 mm full-width half maximum (FWHM) Gaussian kernel.
