In the present study, when merging 480 COGA subjects into SAGE sample, we got highly similar results to previous studies that used SAGE sample alone [5], [22]. The top-ranked risk SNPs (p<10−5) in EAs, AAs, and AAs+EAs in those previous studies [5], [22] were confirmed by our analysis (presented previously [3]). Similarly, many top-ranked risk SNPs (Table S1) in the present study were also listed as top-ranked genes previously. However, these top-ranked genes have not yet been replicated independently and confirmed by functional studies before.
