rVUS and adolescent cannabis use were not associated with ethnicity or zygosity, however younger individuals (age ≤ 21 years) were more likely to report adolescent cannabis use and less likely to report rVUS (Table 1). There was a marginally increased likelihood for MZ twins to report rVUS, relative to their DZ counterparts. With the exception of early age at pregnancy and early age at menstruation which were not associated with rVUS, both rVUS and adolescent cannabis use were associated with all other romantic and reproductive characteristics and covariates. Most prominently, rVUS was related to an almost 3.5 increased odds of ever being pregnant and, even within those reporting a pregnancy, an elevated likelihood of ≥3 pregnancies (OR=1.53, 95% C.I. 1.15-2.03). rVUS was also associated with early sexual debut. The strongest correlates of adolescent cannabis use were early regular use of alcohol and tobacco, as well as early sexual debut.
